This summary contains a list of the evidence
based treatment recommendations for knee OA and includes only less
invasive alternatives to knee replacement. Full text available.
I have summarized it and listed specific
interventions with strenght of evidence provided.
- Exercise – strong evidence for
effectiveness
- NSAIDs – strong evidence for
- Acupuncture – strong evidence
against
- Glucosamine and chondroitin – strong evidence against
- Hyaluronic acid injections – strong evidence against
- Arthroscopy with lavage and debridement – strong evidence against
- Weight loss – moderate evidence for
- Needle lavage – moderate evidence
against
- Lateral wedge insoles – moderate evidence against
- Physical agents (TENS, ultrasound, etc.) – inconclusive
- Manual therapy (chiropractic,
massage) – inconclusive
- Valgus-directing force brace –
inconclusive
- Acetaminophen, opioids, pain patches – inconclusive
- Intraarticular corticosteroid
injections – inconclusive
- Growth factor injections and/or platelet-rich plasma – inconclusive
- Partial meniscectomy in osteoarthritis patients with torn meniscus
– inconclusive
- Valgus-producing proximal tibial osteotomy – limited evidence
- Free-floating interpositional device – no evidence; consensus against
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